Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data
October 9, 2012
Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data
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Title: | Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data |
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Article_Title: | Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data |
Authors: | Adela Elena Joanta, Viorel Miclăuș, Stelian Vasile Sarlea Merca, Vasile Rus, Carmen Socaciu, Nicoleta Decea, Remus Moldovan |
Affiliation: | 1 University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca, Romania 2 University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania |
Abstract: | Increased oxidative stress has been described previously in models of hyperthyroidism and in human subjects with Basedow disease. In this study, the influence of a diet enriched in soy on reactive oxygen species production and on antioxidant defence in hepatic tissue was explored. Soy products are attractive because of their beneficial effects on chronic diseases such as cardiovascular diseases, atherosclerosis, and type II diabetes |
Keywords: | oxidative stress, thyroid hormones, liver, histological alterations |
References: | Ciurdaru V, Andrei S, Pintea A et al, Biochimie medicala veterinara, Metode si tehnici de laborator, Academic Press, Cluj-Napoca, pp. 84- 89, 2001 Corvilain B., Collyn L. & van Sande J, Stimulation by iodide of H2O2 generation in thyroid slices from several species. The Journal of clinical endocrinology and metabolism, 278, pp. 692-699, 2000 Das K, Chainy G B: Modulation of rat liver mitochondrial antioxidant defence system by thyroid hormone. Biochimica et Biophysica acta- Molecular Basis of Disease, 1537: pp. 4439- 4447, 2001 Dróge W, Free radicals in the physiological control of cell function. Physiol Rev, 82: pp. 47-95, 2002 Fernandez V, Videla LA, Biochemical aspects of cellular antioxidant systems. Biol Res 29: pp. 177-182, 1996 Divi RL, Chang HC, Doerge DR, Anti-thyroid isoflavones from soybean: isolation, characterization, and mechanisms of action. Biochem Pharmacol., 54(10): pp. 1087-96, 1994 Joanta A., Clichici S, Filip A, Andrei S, Changes in prooxidant/antioxidant status of hyperthyroid rats treated with Selenium. Central European Journal of Occupational and Environmental Medicine, 11: pp. 123-129, 2005 Joanta A E, Filip A, Clichici S, Andrei S, Daicoviciu D, Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones. Acta Physiologica Hungarica, 93: pp. 347-359, 2006 Martindale JL, Holbrook NJ, Cellular responses to oxidative stress: signaling for suicide and survival. J Cell Physiol 192: pp. 1-15, 2002 Malik R, Mellor N, Selden C, Hodgson A, Triiodothyronine enhances the regenerative capacity of the liver following partial hepatectomy. Hepatology, 1: pp. 79-86, 2003 Nagaoki T, Kaptein E & Berry MJ., Structure- Activity Relationships for Thyroid Hormones Deiodination by Mammalian Type I Iodothyronine Deiodinases. Endocrinology, 138: pp. 213- 219, 2000 Satoh K., Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clinica chimica acta, 90: pp. 37- 43, 1978 Simon BC, Cunningham LD, Cohen RA., Oxidized low density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery. The journal of clinical investigation, 87: pp. 75–79, 1990 Videla, LA, Energy metabolism, thyroid calorigenesis, and oxidative stress: functional and cytotoxic consequences. Redox Rep, 5: pp. 265-275, 2000 Williams, Textbook of Endocrinology: edn 9, pp. 435-456.Eds WB Sounders Company, Philadelphia, 1998 |
Read_full_article: | pdf/18-2008/SU08Joanta.pdf |
Correspondence: | Adela Elena JOANTA, Physiology Department, University of Medicine andPharmacy, Cluj-Napoca, Romania, e-mail: adelaelena@yahoo.com |
Read full article | |
Article Title: | Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data |
Authors: | Adela Elena Joanta, Viorel Miclăuș, Stelian Vasile Sarlea Merca, Vasile Rus, Carmen Socaciu, Nicoleta Decea, Remus Moldovan |
Affiliation: | 1 University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca, Romania 2 University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania |
Abstract: | Increased oxidative stress has been described previously in models of hyperthyroidism and in human subjects with Basedow disease. In this study, the influence of a diet enriched in soy on reactive oxygen species production and on antioxidant defence in hepatic tissue was explored. Soy products are attractive because of their beneficial effects on chronic diseases such as cardiovascular diseases, atherosclerosis, and type II diabetes |
Keywords: | oxidative stress, thyroid hormones, liver, histological alterations |
References: | Ciurdaru V, Andrei S, Pintea A et al, Biochimie medicala veterinara, Metode si tehnici de laborator, Academic Press, Cluj-Napoca, pp. 84- 89, 2001 Corvilain B., Collyn L. & van Sande J, Stimulation by iodide of H2O2 generation in thyroid slices from several species. The Journal of clinical endocrinology and metabolism, 278, pp. 692-699, 2000 Das K, Chainy G B: Modulation of rat liver mitochondrial antioxidant defence system by thyroid hormone. Biochimica et Biophysica acta- Molecular Basis of Disease, 1537: pp. 4439- 4447, 2001 Dróge W, Free radicals in the physiological control of cell function. Physiol Rev, 82: pp. 47-95, 2002 Fernandez V, Videla LA, Biochemical aspects of cellular antioxidant systems. Biol Res 29: pp. 177-182, 1996 Divi RL, Chang HC, Doerge DR, Anti-thyroid isoflavones from soybean: isolation, characterization, and mechanisms of action. Biochem Pharmacol., 54(10): pp. 1087-96, 1994 Joanta A., Clichici S, Filip A, Andrei S, Changes in prooxidant/antioxidant status of hyperthyroid rats treated with Selenium. Central European Journal of Occupational and Environmental Medicine, 11: pp. 123-129, 2005 Joanta A E, Filip A, Clichici S, Andrei S, Daicoviciu D, Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones. Acta Physiologica Hungarica, 93: pp. 347-359, 2006 Martindale JL, Holbrook NJ, Cellular responses to oxidative stress: signaling for suicide and survival. J Cell Physiol 192: pp. 1-15, 2002 Malik R, Mellor N, Selden C, Hodgson A, Triiodothyronine enhances the regenerative capacity of the liver following partial hepatectomy. Hepatology, 1: pp. 79-86, 2003 Nagaoki T, Kaptein E & Berry MJ., Structure- Activity Relationships for Thyroid Hormones Deiodination by Mammalian Type I Iodothyronine Deiodinases. Endocrinology, 138: pp. 213- 219, 2000 Satoh K., Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clinica chimica acta, 90: pp. 37- 43, 1978 Simon BC, Cunningham LD, Cohen RA., Oxidized low density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery. The journal of clinical investigation, 87: pp. 75–79, 1990 Videla, LA, Energy metabolism, thyroid calorigenesis, and oxidative stress: functional and cytotoxic consequences. Redox Rep, 5: pp. 265-275, 2000 Williams, Textbook of Endocrinology: edn 9, pp. 435-456.Eds WB Sounders Company, Philadelphia, 1998 |
*Correspondence: | Adela Elena JOANTA, Physiology Department, University of Medicine andPharmacy, Cluj-Napoca, Romania, e-mail: adelaelena@yahoo.com |