The restoration of some bichemical and immunological parameters after the administration of Echinacea extracts on the wistar rats, consecutive cyclophosphamide therapy

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Article Title:	The restoration of some bichemical and immunological parameters after the administration of Echinacea extracts on the wistar rats, consecutive cyclophosphamide therapy
Authors:	Anca Hermenean, Aurel Ardelean, Coralia Cotoraci
Affiliation:	Faculty of Medicine, “Vasile Goldiș” Western University, Arad, Romania
Abstract:	Cytostatic action, although complex is directed upon divided and young cells, so that, they will especially influence organs and tissues where intense cellular proliferation processes occur. In this paper, we follow both some biochemical and immunological parameters changes after cyclophosphamide administration and rebuilding of these indices after 10 days of Echinacea extracts administration. The administraton of the Echinacea extracts on rats already trated with cyclophosphamide has determined a partial restoration of the seric biochemical parameters. The restoration of the normal levels of the leucocytes treated with Echinacea extracts compaired with the group treated only with cytostatics, shows the restart of the sanguine process of refilling with figurative elements, mostly as a result of the granulocytopoiesis, lymphocytopoiesis and monocytopiesis stimulation at the level of hematogen marrow under the vegetal extract action.
Keywords:	cyclophosphamide, Echinacea extracts, biochemical and immunological parameters
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*Correspondence:	Anca HERMENEAN, Department of Histology, Faculty of Medicine, “Vasile Goldiş” Western University, 91-94 Revolution Avenue, Arad, Romania, e-mail: anca.hermenean@gmail.com