Antimitotic activity of saponins obtained from Anagalis arvensis
October 2, 2012
Antimitotic activity of saponins obtained from Anagalis arvensis
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Title: | Antimitotic activity of saponins obtained from Anagalis arvensis |
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Article_Title: | Antimitotic activity of saponins obtained from Anagalis arvensis |
Authors: | Luciana Dobjanschi, Mariana Mureşan, Angela Antonescu, Mihaela Zdrîncă, Ildiko Szabo, Mircea Tămaş |
Affiliation: | 1 University of Medicine and Pharmacy Oradea, Faculty of Pharmacy 2 University of Medicine and Pharmacy „Iuliu Hatieganu”, Cluj-Napoca |
Abstract: | Because of the extended use of plant derived drugs (Tămaş, 1995), we studied some plant extracts and substances obtained from plants (Tămaş et al., 1978 et al., Tămaş et al., 1983). Natural drugs are used on an extended basis because of limited secondary effects and adverse reactions. In our present paper we tested the action of saponins obtained from Anagalis arvensis (Boiteanu et all, 1964, Glombitza and Kurth, 1987, Amoros and Girre, 1987) on the growth of meristems of Triticum sp. and cellular division. Tests with saponins obtained from Anagalis arvensis inhibit the growth of Triticum sp. meristems, and cellular division, concluding that these saponins may be included in the antimitotic medication group (Schonfelder and Schonfelder, 2004). |
Keywords: | saponins, anagalis arvensis, antimitotics |
References: | Amoros M., Girre R. L., Structure of two antiviral triterpene saponins from Anagallis arvensis, Phytochemistry, 26, (3), pp. 787-791, 1987. Arieşan Maria, Pitea Michaela, Cojocaru Zenaida, Acţiunea pe teste fitobiologice a unor derivaţi 7- R-flavonici, Symposium flavonoide, Cluj-Napoca VI., p. 54, 1984. Boiteau P., Pasich B., Ratsimamanga r.a., Les triterpenoides en physiologie vegetale et animale, Gauthier-Villars, Paris, 1964. Glombitza K.W. und Kurth H., Die Struktur einiger Triterpensaponine aus Anagallis arvensis, Planta Medica, 53 (6), p. 509, 1987. Schönfelder I., Schönfelder P., Das neue handbuch der Heilpflanzen, botanik arzneidrogen Wirkstoffe anwendungen, Stuttgart, 420, 2004. Şerbănescu-Jitariu Gabriela, Andrei Maria, Rădulescu- Mitroiu Natalia, Petria Elena, Practicum de biologie vegetală, Ed. Ceres, Buc., pp. 158-225, 1983. Tarnavschi ION T., Şerbănescu-Jitariu Gabriela, Mitroiu Rădulescu Natalia, rădulescu Didona, Practicum de morfologie şi anatomie vegetală, Bucureşti, 1974. Tarnavschi Ion T., Şerbănescu-Jitariu Gabriela, Mitroiu.Rădulescu Natalia, Rădulescu Didona, Practicum de morfologie şi anatomie vegetală, ediţia a 2-a, Bucureşti, 1981. Tămaş M., Actualităţi în fitoterapie: taxolul, Terapeutica, vol. 2, 3, 40, 1995. Tămaş M., Hodişan V., Grecu L. Făgărăşanu E., Baciu M., Muică I., Cercetări asupra saponinelor triterpenice din plante medicinale indigene, Studii şi cercetări de biochimie, 21, (1), pp. 89-94, 1978. Tămaş M., Hodişan Viorica, Saponine triterpenice de interes terapeutic, Practica farmaceutică, p. 57, 1983. Tămaş M., Lucrări practice de biologie celulară, Lit. IMF Cluj-Napoca, 1976 |
Read_full_article: | pdf/18-2008/SU08Dobjanschi2.pdf |
Correspondence: | Dobjanschi Luciana, Facultatea de Medicina si Farmacie Oradea, Catedra de Biochimie, P-ta 1 Decembrie nr. 10, Tel. 0723-766789, email: dobjanschil@yahoo.com |
Read full article | |
Article Title: | Antimitotic activity of saponins obtained from Anagalis arvensis |
Authors: | Luciana Dobjanschi, Mariana Mureşan, Angela Antonescu, Mihaela Zdrîncă, Ildiko Szabo, Mircea Tămaş |
Affiliation: | 1 University of Medicine and Pharmacy Oradea, Faculty of Pharmacy 2 University of Medicine and Pharmacy „Iuliu Hatieganu”, Cluj-Napoca |
Abstract: | Because of the extended use of plant derived drugs (Tămaş, 1995), we studied some plant extracts and substances obtained from plants (Tămaş et al., 1978 et al., Tămaş et al., 1983). Natural drugs are used on an extended basis because of limited secondary effects and adverse reactions. In our present paper we tested the action of saponins obtained from Anagalis arvensis (Boiteanu et all, 1964, Glombitza and Kurth, 1987, Amoros and Girre, 1987) on the growth of meristems of Triticum sp. and cellular division. Tests with saponins obtained from Anagalis arvensis inhibit the growth of Triticum sp. meristems, and cellular division, concluding that these saponins may be included in the antimitotic medication group (Schonfelder and Schonfelder, 2004). |
Keywords: | saponins, anagalis arvensis, antimitotics |
References: | Amoros M., Girre R. L., Structure of two antiviral triterpene saponins from Anagallis arvensis, Phytochemistry, 26, (3), pp. 787-791, 1987. Arieşan Maria, Pitea Michaela, Cojocaru Zenaida, Acţiunea pe teste fitobiologice a unor derivaţi 7- R-flavonici, Symposium flavonoide, Cluj-Napoca VI., p. 54, 1984. Boiteau P., Pasich B., Ratsimamanga r.a., Les triterpenoides en physiologie vegetale et animale, Gauthier-Villars, Paris, 1964. Glombitza K.W. und Kurth H., Die Struktur einiger Triterpensaponine aus Anagallis arvensis, Planta Medica, 53 (6), p. 509, 1987. Schönfelder I., Schönfelder P., Das neue handbuch der Heilpflanzen, botanik arzneidrogen Wirkstoffe anwendungen, Stuttgart, 420, 2004. Şerbănescu-Jitariu Gabriela, Andrei Maria, Rădulescu- Mitroiu Natalia, Petria Elena, Practicum de biologie vegetală, Ed. Ceres, Buc., pp. 158-225, 1983. Tarnavschi ION T., Şerbănescu-Jitariu Gabriela, Mitroiu Rădulescu Natalia, rădulescu Didona, Practicum de morfologie şi anatomie vegetală, Bucureşti, 1974. Tarnavschi Ion T., Şerbănescu-Jitariu Gabriela, Mitroiu.Rădulescu Natalia, Rădulescu Didona, Practicum de morfologie şi anatomie vegetală, ediţia a 2-a, Bucureşti, 1981. Tămaş M., Actualităţi în fitoterapie: taxolul, Terapeutica, vol. 2, 3, 40, 1995. Tămaş M., Hodişan V., Grecu L. Făgărăşanu E., Baciu M., Muică I., Cercetări asupra saponinelor triterpenice din plante medicinale indigene, Studii şi cercetări de biochimie, 21, (1), pp. 89-94, 1978. Tămaş M., Hodişan Viorica, Saponine triterpenice de interes terapeutic, Practica farmaceutică, p. 57, 1983. Tămaş M., Lucrări practice de biologie celulară, Lit. IMF Cluj-Napoca, 1976 |
*Correspondence: | Dobjanschi Luciana, Facultatea de Medicina si Farmacie Oradea, Catedra de Biochimie, P-ta 1 Decembrie nr. 10, Tel. 0723-766789, email: dobjanschil@yahoo.com |