The relationship between blood groups and COVID disease in Tulcea County
December 26, 2024
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| Article Title: | The relationship between blood groups and COVID disease in Tulcea County |
| Authors: | Nistor V., Turcuș V., Máthé E., Bratosin D. |
| Affiliation: | Department of Biology and Life Sciences, Faculty of Medicine, „Vasile Goldis” Western University of Arad, Arad, Romania Tulcea County Hospital, Tulcea, Romania |
| Abstract: | Human OAB blood-type antigens exhibit alternative phenotypes and genetically derived glycoconjugate structures that are located on the red cell surface which play an active role in the cells’ physiology, pathology, and cellular molecular recognition. The OAB blood group system is associated with several parameters of healthy aging and disease development. The aim of our studies was to define the possible relationship between the blood group mosaic and the ability to allow the attachment of the SARS-CoV-2 virus due to antigens present on erythrocytes. The number of those infected with COVID-19 is 0.1% lower among those with blood group O and 0.5% higher among those infected with A compared to the area average, and for those with B, we have 1.2% more infected. However, for those in AB, the difference is significant contrary to theories, with 1.6% less infected compared to the area average. The results of our study cannot fully support theories suggesting the protective capacity of blood type O and that individuals with blood types A, B, and AB have a higher risk of contracting COVID-19 and/or making it more severe of the disease. Regarding the Rh system, our results show that the number of people Rh positive infected with the SARS-CoV-2 virus was 2.3% higher than Rh negative meaning that there is protection in individuals who do not possess the Rh antigen, possibly because the virus uses the antigen D to enter the host cell. |
| Keywords: | blood groups, sars-cov-2 virus, COVID disease, Tulcea county. |
| *Correspondence: | Valentina Nistor, „Vasile Goldiş” Western University of Arad, Faculty of Medicine, Department of Biology and Life Sciences, Arad, Str. Liviu Rebreanu, nr. 86, Arad, Romania, email: nistorvalentina23@gmail.com. |
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