The risk of urinary infection in Prune-Belly syndrome in children – case study

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Article Title:	The risk of urinary infection in Prune-Belly syndrome in children – case study
Authors:	Viorica Leordean, Lazar Dorin
Affiliation:	“Vasile Goldis” Western University, Arad, Romania Clinic of Pediatrics II, Faculty of Medicine, Pharmacy and Dental Medicine
Abstract:	The author presents a case study on the evolution of three children enrolled in Prune-Belly syndrome. This syndrome is a complex dysplasia, a rare pathology in children, characterized by the triad – the classic – hypo- or aplasia of righteous abdominal, cryptorchidism, abnormality of the urinary tract; also, it can be associated with pulmonary, cardiac, digestive, osteoarticular, and other malformations. Diagnostic criteria and etiopathogeny aspects are presented showing embryopathy and X-linked hereditary transmission theories as the most plausible. Analyzing therapeutic aspects, it is stressed that medical treatment precedes or follows surgery, which cannot resolve urinary infection unless dysplastic urinary reconstruction is performed. Serious forms of Prune-Belly syndrome have a development and poor prognosis. Intrauterine and neonatal mortality is 20% and 50% in the first 2 years of life. The risk of urinary infection and / or lungs burdens the patient’s clinical condition, allowing further appreciation on evolution of the disease. For cases solvable by plastic surgical reconstruction, as those who respond to medical therapy, differentiation will be monitored in territory and check-ups by the specialized consulting room from Policlinic Health Center. Urinary infection relapse danger is permanent, requiring differentiated supervision. This three cases interest practitioners, by at least two aspects: the rarity of the disease, and complexity of dysplasia constituent, which has serious implications on the body economy.
Keywords:	urinary infection, prune-belly syndrome
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