Aronia Melanocarpa, a potential therapeutic agent


Aronia Melanocarpa, a potential therapeutic agent

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Title: Aronia Melanocarpa, a potential therapeutic agent
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Article_Title: Aronia Melanocarpa, a potential therapeutic agent
Authors: Ioana Lancrajan
Affiliation: „Vasile Goldiş” Western University of Arad, Faculty of Life Sciences, Romania
Abstract: The positive effect of Aronia melanocarpa on human healthy is well known from over hundred years with a global and targeted action direct on certain organs and systems as cardiovascular system, age associated diseases, with prodigious results regarding cancer treatment, especially gastro-intestinal cancer (Slimestad, 2005/ Grajek, 2004). The absolute positive tendency of Aronia plant on humans is well known, however the variant originated from Nordh America lies in attention of different researchers groups beginning 1990 years. Our clinical tests regarding the impact on the arterial hypertension and hypercholesterolemia, regulation of lipid equilibrium are encouraging. Our data establish the biggest microelements content of Chokeberry (Aronia) against other fruits as sour cherry (Prunus cerasus), wine grapes (Vitis vinifera), Rubus caesius, Vaccinium myrtillus and Rosa canina. Favorable action on blood glucose level is also reported as clinical result. Our findings imply a start point for future investigations in order to elaborate new drugs based on Aronia plant extracts.
Keywords: glycaemia, minerals, vitamins, cholesterol, Chokeberry, Aronia
References: Ara DV 2002, Schwarzfruchtige Aroinia: gesund-und „bald in alle Munde”?, Flussiges Obst 10: 653-658
Borrisova R, Valcheva S 1994, Antiinflamatory effect of flavonoids in the natural juice drom Aronia melanocarpa, rutin and rutin-mafgnesium complex on an experimental model of inflamation induced by histamine and serotonin. Acta Physiologica et Pharmacologica Bulgarica 20 (1): 25-30
Broncel M, Koziróg-Kołacińska M, Andryskowski G, Duchnowicz P, Koter-Michalak M, Owczarczyk A,
He J et al 2006, Intact anthocyanins and metabolites in rat urine and plasma after 3 months of anthocyanin supplementation. Nutrition and cancer 54 (1): 3-12
Chojnowska-Jezierska J. 2007, Effect of anthocyanins from Aronia melanocarpa on blood pressure, concentration of endothelin-1 and lipids in patients with metabolic syndrome, Pol Merkur Lekarski. 23(134):116-9.
Jappson N 2000, The effect of cultivarand cracking on fruit quality in black Chokeberry and hybrids between Chokeberry and Rowan (Sorbus), Gartenbauwissenschaften 65(2) : 93-98
Kulling SE, Harshadai M. Rawel 2008, Chokeberry (Aronia melanocarpa) – A Review on the Characteristic Components and Potential Health Effects, Planta Med 74: 1625–1634
Kowalzky E et al 2003, Effect of anthocynins on selected biochemical parameters in rats exposed to cadmium
Acta biochemica Polonica 50(2):543-8
Kay T et al 2004, Anthocyanins metabolites in human urine and serum, British Journal of Nutrition 91(6): 933-42
Kedzierska M, Olas B, Wachowicz B, Stochmal A, Oleszek W, Jeziorski A, Piekarski J, 2010, The nitrative and oxidative stress in blood platelets isolated from breast cancer patients: The protectory action of aronia melanocarpa extract, Journal of Complementary and Integrative Medicine 21 (7 ): 541-548
Pilaczynska-Szczesniak L et al 2005, The influence of chokerberry juice supplementation on teh reduction of oxidative stress resulting from an incremental rowing ergometrer exercise, International Journal of sport nutrition and exercise metabolim 15 (12):48-58
Slimestad R etal 2005, Flavonoids from black chokoberies, Aronia melanocarpa, Journal of food composition and analysis 18: 61-68
Simeonov SB et al 2002, Effects of Aronia Melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia med (Plovdiv) 44(3):20-3
Valcheva-Kuzmanova S et al 2006, Antihyperlipemic effect of Aronia melanocarpa fruit juice in rat fed a high colesterol diet, Plant food for human nutrition 62 (1): 19-24
Valcheva-Kuzmanova S et al 2005, Effect of Aronia melanocarpa fruit juice on indomethacion induced gastric mucosal damage and oxidative stress in rats, Experimental and toxicologic pathology 56(6):385-92
http://www.ars.usda.gov/Services/docs.htm?docid=15866
http://www.ncbi.nlm.nih.gov/pubmed/12580526
Read_full_article: pdf/22-2012/22-3-2012/SU22-3-2012-Lancrajan.pdf
Correspondence: Ioana Lancrajan, „Vasile Goldiş” Western University of Arad, Faculty of Life Sciences, Rebreanu str. 91-93; email: Lancrajan _ioana@yahoo.com

Read full article
Article Title: Aronia Melanocarpa, a potential therapeutic agent
Authors: Ioana Lancrajan
Affiliation: „Vasile Goldiş” Western University of Arad, Faculty of Life Sciences, Romania
Abstract: The positive effect of Aronia melanocarpa on human healthy is well known from over hundred years with a global and targeted action direct on certain organs and systems as cardiovascular system, age associated diseases, with prodigious results regarding cancer treatment, especially gastro-intestinal cancer (Slimestad, 2005/ Grajek, 2004). The absolute positive tendency of Aronia plant on humans is well known, however the variant originated from Nordh America lies in attention of different researchers groups beginning 1990 years. Our clinical tests regarding the impact on the arterial hypertension and hypercholesterolemia, regulation of lipid equilibrium are encouraging. Our data establish the biggest microelements content of Chokeberry (Aronia) against other fruits as sour cherry (Prunus cerasus), wine grapes (Vitis vinifera), Rubus caesius, Vaccinium myrtillus and Rosa canina. Favorable action on blood glucose level is also reported as clinical result. Our findings imply a start point for future investigations in order to elaborate new drugs based on Aronia plant extracts.
Keywords: glycaemia, minerals, vitamins, cholesterol, Chokeberry, Aronia
References: Ara DV 2002, Schwarzfruchtige Aroinia: gesund-und „bald in alle Munde”?, Flussiges Obst 10: 653-658
Borrisova R, Valcheva S 1994, Antiinflamatory effect of flavonoids in the natural juice drom Aronia melanocarpa, rutin and rutin-mafgnesium complex on an experimental model of inflamation induced by histamine and serotonin. Acta Physiologica et Pharmacologica Bulgarica 20 (1): 25-30
Broncel M, Koziróg-Kołacińska M, Andryskowski G, Duchnowicz P, Koter-Michalak M, Owczarczyk A,
He J et al 2006, Intact anthocyanins and metabolites in rat urine and plasma after 3 months of anthocyanin supplementation. Nutrition and cancer 54 (1): 3-12
Chojnowska-Jezierska J. 2007, Effect of anthocyanins from Aronia melanocarpa on blood pressure, concentration of endothelin-1 and lipids in patients with metabolic syndrome, Pol Merkur Lekarski. 23(134):116-9.
Jappson N 2000, The effect of cultivarand cracking on fruit quality in black Chokeberry and hybrids between Chokeberry and Rowan (Sorbus), Gartenbauwissenschaften 65(2) : 93-98
Kulling SE, Harshadai M. Rawel 2008, Chokeberry (Aronia melanocarpa) – A Review on the Characteristic Components and Potential Health Effects, Planta Med 74: 1625–1634
Kowalzky E et al 2003, Effect of anthocynins on selected biochemical parameters in rats exposed to cadmium
Acta biochemica Polonica 50(2):543-8
Kay T et al 2004, Anthocyanins metabolites in human urine and serum, British Journal of Nutrition 91(6): 933-42
Kedzierska M, Olas B, Wachowicz B, Stochmal A, Oleszek W, Jeziorski A, Piekarski J, 2010, The nitrative and oxidative stress in blood platelets isolated from breast cancer patients: The protectory action of aronia melanocarpa extract, Journal of Complementary and Integrative Medicine 21 (7 ): 541-548
Pilaczynska-Szczesniak L et al 2005, The influence of chokerberry juice supplementation on teh reduction of oxidative stress resulting from an incremental rowing ergometrer exercise, International Journal of sport nutrition and exercise metabolim 15 (12):48-58
Slimestad R etal 2005, Flavonoids from black chokoberies, Aronia melanocarpa, Journal of food composition and analysis 18: 61-68
Simeonov SB et al 2002, Effects of Aronia Melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus, Folia med (Plovdiv) 44(3):20-3
Valcheva-Kuzmanova S et al 2006, Antihyperlipemic effect of Aronia melanocarpa fruit juice in rat fed a high colesterol diet, Plant food for human nutrition 62 (1): 19-24
Valcheva-Kuzmanova S et al 2005, Effect of Aronia melanocarpa fruit juice on indomethacion induced gastric mucosal damage and oxidative stress in rats, Experimental and toxicologic pathology 56(6):385-92
http://www.ars.usda.gov/Services/docs.htm?docid=15866
http://www.ncbi.nlm.nih.gov/pubmed/12580526
*Correspondence: Ioana Lancrajan, „Vasile Goldiş” Western University of Arad, Faculty of Life Sciences, Rebreanu str. 91-93; email: Lancrajan _ioana@yahoo.com