Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data

Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data

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Title: Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data
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Article_Title: Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data
Authors: Adela Elena Joanta, Viorel Miclăuș, Stelian Vasile Sarlea Merca, Vasile Rus, Carmen Socaciu, Nicoleta Decea, Remus Moldovan
Affiliation: 1 University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca, Romania
2 University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania
Abstract: Increased oxidative stress has been described previously in models of hyperthyroidism and in
human subjects with Basedow disease. In this study, the influence of a diet enriched in soy on reactive oxygen species production and on antioxidant defence in hepatic tissue was explored. Soy products are attractive because of their beneficial effects on chronic diseases such as cardiovascular diseases, atherosclerosis, and type II diabetes
Keywords: oxidative stress, thyroid hormones, liver, histological alterations
References: Ciurdaru V, Andrei S, Pintea A et al, Biochimie medicala veterinara, Metode si tehnici de laborator, Academic Press, Cluj-Napoca, pp. 84- 89, 2001
Corvilain B., Collyn L. & van Sande J, Stimulation by iodide of H2O2 generation in thyroid slices from several species. The Journal of clinical endocrinology and metabolism, 278, pp. 692-699, 2000
Das K, Chainy G B: Modulation of rat liver mitochondrial antioxidant defence system by thyroid hormone. Biochimica et Biophysica acta- Molecular Basis of Disease, 1537: pp. 4439- 4447, 2001
Dróge W, Free radicals in the physiological control of cell function. Physiol Rev, 82: pp. 47-95, 2002
Fernandez V, Videla LA, Biochemical aspects of cellular antioxidant systems. Biol Res 29: pp.
177-182, 1996
Divi RL, Chang HC, Doerge DR, Anti-thyroid isoflavones from soybean: isolation, characterization, and mechanisms of action. Biochem Pharmacol., 54(10): pp. 1087-96, 1994
Joanta A., Clichici S, Filip A, Andrei S, Changes in prooxidant/antioxidant status of hyperthyroid
rats treated with Selenium. Central European Journal of Occupational and Environmental Medicine, 11: pp. 123-129, 2005
Joanta A E, Filip A, Clichici S, Andrei S, Daicoviciu D, Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones. Acta Physiologica Hungarica, 93: pp. 347-359, 2006
Martindale JL, Holbrook NJ, Cellular responses to oxidative stress: signaling for suicide and
survival. J Cell Physiol 192: pp. 1-15, 2002
Malik R, Mellor N, Selden C, Hodgson A, Triiodothyronine enhances the regenerative capacity of the liver following partial hepatectomy. Hepatology, 1: pp. 79-86, 2003
Nagaoki T, Kaptein E & Berry MJ., Structure- Activity Relationships for Thyroid Hormones
Deiodination by Mammalian Type I Iodothyronine Deiodinases. Endocrinology, 138: pp. 213- 219, 2000
Satoh K., Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric
method. Clinica chimica acta, 90: pp. 37- 43, 1978
Simon BC, Cunningham LD, Cohen RA., Oxidized low density lipoproteins cause contraction and
inhibit endothelium-dependent relaxation in the pig coronary artery. The journal of clinical
investigation, 87: pp. 75–79, 1990
Videla, LA, Energy metabolism, thyroid calorigenesis, and oxidative stress: functional and cytotoxic
consequences. Redox Rep, 5: pp. 265-275, 2000
Williams, Textbook of Endocrinology: edn 9, pp. 435-456.Eds WB Sounders Company, Philadelphia, 1998
Read_full_article: pdf/18-2008/SU08Joanta.pdf
Correspondence: Adela Elena JOANTA, Physiology Department, University of Medicine andPharmacy, Cluj-Napoca, Romania, e-mail: adelaelena@yahoo.com

Read full article
Article Title: Phytotherapeutical alternatives in preventing oxidative stress disorders due to hyperthyroidismexperimental data
Authors: Adela Elena Joanta, Viorel Miclăuș, Stelian Vasile Sarlea Merca, Vasile Rus, Carmen Socaciu, Nicoleta Decea, Remus Moldovan
Affiliation: 1 University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj-Napoca, Romania
2 University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania
Abstract: Increased oxidative stress has been described previously in models of hyperthyroidism and in
human subjects with Basedow disease. In this study, the influence of a diet enriched in soy on reactive oxygen species production and on antioxidant defence in hepatic tissue was explored. Soy products are attractive because of their beneficial effects on chronic diseases such as cardiovascular diseases, atherosclerosis, and type II diabetes
Keywords: oxidative stress, thyroid hormones, liver, histological alterations
References: Ciurdaru V, Andrei S, Pintea A et al, Biochimie medicala veterinara, Metode si tehnici de laborator, Academic Press, Cluj-Napoca, pp. 84- 89, 2001
Corvilain B., Collyn L. & van Sande J, Stimulation by iodide of H2O2 generation in thyroid slices from several species. The Journal of clinical endocrinology and metabolism, 278, pp. 692-699, 2000
Das K, Chainy G B: Modulation of rat liver mitochondrial antioxidant defence system by thyroid hormone. Biochimica et Biophysica acta- Molecular Basis of Disease, 1537: pp. 4439- 4447, 2001
Dróge W, Free radicals in the physiological control of cell function. Physiol Rev, 82: pp. 47-95, 2002
Fernandez V, Videla LA, Biochemical aspects of cellular antioxidant systems. Biol Res 29: pp.
177-182, 1996
Divi RL, Chang HC, Doerge DR, Anti-thyroid isoflavones from soybean: isolation, characterization, and mechanisms of action. Biochem Pharmacol., 54(10): pp. 1087-96, 1994
Joanta A., Clichici S, Filip A, Andrei S, Changes in prooxidant/antioxidant status of hyperthyroid
rats treated with Selenium. Central European Journal of Occupational and Environmental Medicine, 11: pp. 123-129, 2005
Joanta A E, Filip A, Clichici S, Andrei S, Daicoviciu D, Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones. Acta Physiologica Hungarica, 93: pp. 347-359, 2006
Martindale JL, Holbrook NJ, Cellular responses to oxidative stress: signaling for suicide and
survival. J Cell Physiol 192: pp. 1-15, 2002
Malik R, Mellor N, Selden C, Hodgson A, Triiodothyronine enhances the regenerative capacity of the liver following partial hepatectomy. Hepatology, 1: pp. 79-86, 2003
Nagaoki T, Kaptein E & Berry MJ., Structure- Activity Relationships for Thyroid Hormones
Deiodination by Mammalian Type I Iodothyronine Deiodinases. Endocrinology, 138: pp. 213- 219, 2000
Satoh K., Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric
method. Clinica chimica acta, 90: pp. 37- 43, 1978
Simon BC, Cunningham LD, Cohen RA., Oxidized low density lipoproteins cause contraction and
inhibit endothelium-dependent relaxation in the pig coronary artery. The journal of clinical
investigation, 87: pp. 75–79, 1990
Videla, LA, Energy metabolism, thyroid calorigenesis, and oxidative stress: functional and cytotoxic
consequences. Redox Rep, 5: pp. 265-275, 2000
Williams, Textbook of Endocrinology: edn 9, pp. 435-456.Eds WB Sounders Company, Philadelphia, 1998
*Correspondence: Adela Elena JOANTA, Physiology Department, University of Medicine andPharmacy, Cluj-Napoca, Romania, e-mail: adelaelena@yahoo.com