SCImago Journal & Country Rank

Ranking and Indexing

Index Copernicus Value (2010): 5.45
CNCSIS B+ (code 820) since 2007

International Databases:
SCOPUS since 2009
EBSCO Academic Search Complete since 2008
Index Copernicus Journals Master List since 2009
Directory of Open Access Journals (DOAJ) since 2008
Genamics JournalSeek since 18/2008

International Catalogues:
Oxford University's Library since 2003

Journal Info

Title: Studia Universitatis Vasile Goldis, Seria Stiintele Vietii (Life Sciences Series)
Abbreviated title: Studia Univ. VG, SSV
Publisher: "Vasile Goldis" University Press
Owner: Western University "Vasile Goldis" Arad, Romania
ISSN: 1584-2363
e-ISSN: 1842-7863
ISSN-L: 1584-2363

Who's Online

We have 103 guests online

Index Databases

Phytotherapy, an alternative in the treatment of rheumatic infections Print E-mail
Written by Munteanu M.F., Tuduce P., Daraban A.M., Pribac C.   
Read full article
Article Title: Phytotherapy, an alternative in the treatment of rheumatic infections
Authors: M.F. Munteanu, P. Tuduce, A.M. Dărăban, C. Pribac
Affiliation: 1.Department of Pharmacognosy, „Vasile Goldiş” Western University, Arad;
2. Department of Balneophysiotherapy and rehabilitation therapy, „Vasile Goldiş” Western University, Arad;
3. Department of General and Inorganic Chemistry, „Vasile Goldiş” Western University, Arad;
4. Department of Cell and Molecular Biology, „Vasile Goldiş” Western University, Arad
Abstract: The traditional medicine has been using plants for centuries for treating different rheumatic troubles and joint pains. Harpagophytum is an alternative in treating the rheumatic inflammatory diseases. The studies of numerous researchers show the anti-inflammatory and analgesic properties of this species. This study aims to be a synthesis of the data published so far in relation to Harpagophytum procumbens. The anti-inflammatory and analgesic properties are based on the plant composition of glycosides. According to the study Harpagophytum exercises the anti-inflammatory and analgesic action by blocking the cyclooxygenase 2 and the nitric oxide followed by the blocking of the formation of prostaglandins (the inflammation and pain being mediated by the prostaglandins at the level of the inflammatory tissues). The use of Harpagophytum in case of inflammatory or degenerative rheumatism brings about the improvement of the symptoms and represents a viable alternative to the medication with non-steroidal anti-inflammatory drugs.
Keywords: Harpagophytum procumbens, osteoarthritis, cyclooxygenase
References: 1. Wikipedia; Free encicolpedia.
2. Leblan D., Chantre P., Fournié B., “Harpagophytum procumbens in the treatment of knee and hip osteoarthritis. Four-month results of a prospective, multicenter, double-blind trial versus diacerhein.”, Joint Bone Spine. 2000;67(5):462-7. PMID: 11143915 [PubMed - indexed for MEDLINE]
3. Chrubasik S. , Model A. , Negru A., Pollak S., “A double-compared Doloteffin ® and Vioxx ® random blind study in the treatment of lumbar pain”, Journal of Rheumatology from Germany (2003) 42 (1):. 141 - 148DOI: Online ISSN 1462-0332
4. Mi-Hyeon Jang, Sabina Lim, Seung-Moo Han, Hi-Joon Park, Insop Shin, Jin-Woo Kim, Nam-Jae Kim, Ji-Suk Lee, Kyung-Ah Kim and Chang-Ju Kim, “Harpagophytum procumbens Suppresses Lipopolysaccharide - Stimulated Expressions of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in Fibroblast Cell Line L929” Journal of Pharmacological Sciences Vol. 93 (2003) , No. 3 pp.367-371
5. Whitehouse LW, Znamirowska M, Paul CJ. Devil’s Claw (Harpagophytum procumbens): no evidence for anti-inflammatory activity in the treatment of arthritic disease. Canadian Medical Association Journal 1983; 129:249-51.
6. Lanhers MC, Fleurentin J, Mortier F, Vinche A, Younos C. Anti-inflammatory and analgesic effects of an aqueous extract of Harpagophytum procumbens. Planta Medica 1992; 58:117-23.
7. Jadot G, Lecomte A. Activite anti-inflammatoire d’Harpagophytum procumbens DC. Lyon. Mediterraneee Medical Medecine du Sud-Est 1992; 28:833-5.
8. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A guide for Health-care Professionals. London: The Pharmaceutical Press, 1996:296.
9. Chrubasik J., “Zur Knorpelprotektion von Harpagophytum procumbens DC : Histologische, zellbiologische und molekularbiologische Untersuchungen” (2006) Phytomedicine. 13. 2006, 598-600
10. Compendium of rheumatology, Eugen D. Popescu, Ruxandra Ionescu, Editia a-III-a actualizata si adaugita; Technica Publishing House, Bucharest 2002;ISBN 973-31-2143-6; pp 75
11. Recio M, Giner R, Manez S, Rios J. Structural considerations on the iridoids as anti-inflammatory agents.Planta Medica 1994; 60:232-4.
12. Belaiche P. Etude clinique de 630 cas d‘artrose traites par le nebulisat aqueux d‘Harpagophytum procumbens (Radix). Phytotherapy 1982; 1:22-28.
13. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physicians‘ Guide to Herbal Medicine. Berlin: Springer, 1997:306.